COMPARE: Clinical Optimization with Modular Planning and Assessment via RAG-Enhanced AI-OCT: Superior Decision Support for Percutaneous Coronary Intervention Compared to ChatGPT-5 and Junior Operators
By: Wei Fang, Chiyao Wang, Wenshuai Ma, Hui Liu, Jianqiang Hu, Xiaona Niu, Yi Chu, Mingming Zhang, Jingxiao Yang, Dongwei Zhang, Zelin Li, Pengyun Liu, Jiawei Zheng, Pengke Zhang, Chaoshi Qin, Wangang Guo, Bin Wang, Yugang Xue, Wei Zhang, Zikuan Wang, Rui Zhu, Yihui Cao, Quanmao Lu, Rui Meng, Yan Li
Published: 2025-12-11
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Abstract
This paper introduces CA-GPT, a RAG-enhanced AI-OCT system, demonstrating superior decision support for Percutaneous Coronary Intervention (PCI). It significantly outperforms general-purpose large language models like ChatGPT-5 and junior physicians in both PCI planning and assessment phases, providing a standardized and reliable method for intravascular imaging interpretation and augmenting operator expertise.