DeepER-Med: Advancing Deep Evidence-Based Research in Medicine Through Agentic AI

By: Anya Sharma, Ben Carter, Clara Dixon, Ethan Foster, Grace Hall

Published: 2026-04-20

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Abstract

This paper proposes the DeepER-Med framework, an agentic AI system designed to significantly enhance deep evidence-based research in medicine. It focuses on integrating certainty calibration with retrieval-based search for open-domain question answering, aiming to improve reliability and transparency in healthcare and biomedical discovery. The system performs multi-step reflection and verification over Wikipedia data, trained with reinforcement learning for optimal performance in real-world clinical scenarios.

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DeepER-Med: Advancing Deep Evidence-Based Research in Medicine Through Agentic AI | ArXiv Intelligence